There can be no one revered before the LordJesusChrist. Jesus is echoing the eternal requirement by His HolySpirit that He be the source, the substance and the end of our lives.

To not value the HolySpirit as such makes a person unworthy of Him.

It is very difficult to make a choice which causes us to break fellowship with our parents, siblings and children. But Christ demands our commitment to follow Him whatever the cost.